1. B.Sc in Chemistry (Hons.) from The University of Burdwan in 2007
2. M.Sc in Chemistry (Organic Chemistry) from Jadavpur University, Kolkata, India in 2009
3. PhD in Chemistry from Indian Institute of Technology Kharagpur (IITKGP), India in 2015
Work Experiences
1. Postdoctoral Research Associate; Institute: Texas A&M University College Station, Tx-77843, USA; Duration: 28/09/2015 - 31/07/2018
2. Assistant Research Scientist; Institute: Texas A&M University College Station, Tx-77843, USA; Duration: 01/08/2018 - 04/02/2019
3. Assistant Professor, Department of Chemitsry, National Institute of Technology Durgapur, India. Duration: 19/02/2019-ongoing
Research Interest
Main Topics: Medicinal Chemistry, Chemical sensors
Research area: The overall goal of my research lab is to develop and apply novel technologies to address the issues at the interface of chemistry and biology, and to break the wall between these two. By combining research expertise in organic synthesis, Computater-aided Drug Design (CADD), and biophysical/biochemical techniques, my research lab use chemical biology approach to discover inhibitor targeting cancer and Alzheimer's Disease. Additionally, we design and synthesize sensors for biologically relevant metals and biomolecules.
Projects
Title
Investigator
Co-investigator
Sponsered Agency
Duration
Status
Development of epigenetic drugs
Dr Deb Ranjan Banerjee
Research Initiation Grant (RIG) NIT Durgapur
2019-2021
Completed
NMR Studies of Lys/Arg side chain interactions in epigenetics and membrane induced dimerization
Dr Deb Ranjan Banerjee
Prof Miquel Pons, University of Barcelona
SERB-SIRE grant
2022
ongoing
Teachings
UG Courses:
1. Biochemistry: Structure and function (CYC 401), Even Sem (2019-ongoing), Approx 20 students/sem (Solo theory course)
2. Natural Products and Drug Design (CYE932), Odd Sem (2019-ongoing), Approx 10 students/sem (Solo theory course)
3. Non-Equilibrium Thermodynamics and Biophysical Chemistry (CYE912), Odd sem (2019-ongoing), approx 10 students/sem (Shared theory course)
4. Bioorganic Chemistry (CYE933), Odd Sem (2019-ongoing), Approx 10 students/sem (Shared theory course)
5. Engineering Chemistry (CYC01), Even&Odd sem (2019-ongoing), approx 80-90 students/sem (Shared theory course)
6. Biochemistry laboratory (CYS453), Even sem (2019-ongoing), approx 20 students/sem
7. Quantitative Analysis of Organic Samples (CYS553), Odd sem (2019-ongoing), approx 20 students/sem
8. Single Step Synthesis of Organic Compounds (CYS 653), Even sem (2019-ongoing), approx 20 students/sem
PG Courses:
1. Structure and function of biomolecules (CY 3101), Odd Sem (2019-ongoing), Approx 25 students/sem (Solo theory course)
2. Natural Products and Drug Design (CY9132), Odd Sem (2019-ongoing), Approx 10 students/sem (Solo theory course)
3. Bioorganic Chemistry (CY9133), Odd Sem (2019-2022), Approx 10 students/sem (Shared theory course)
4. Non-Equilibrium Thermodynamics and Biophysical Chemistry (CY9112), Odd sem (2019-ongoing), approx 10 students/sem (Shared theory course)
UG / PG Students
DEBASHREE KAUDI
ORGANIC SYNTHESIS AND Chemical Sensor
DEBASHREE KAUDI
ORGANIC SYNTHESIS AND Chemical Sensor
VIKRANT SINGH
ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY
VIKRANT SINGH
ORGANIC SYNTHESIS AND MEDICINAL CHEMISTRY
SUBHRAJIT CHOWDHURY
Computer-Aided Drug Design (CADD)
SUBHRAJIT CHOWDHURY
Computer-Aided Drug Design (CADD)
PIYUSH TIWARI
PIYUSH TIWARI
ARPITA PADHAN
ARPITA PADHAN
SARBAJIT LAYEK
SARBAJIT LAYEK
DOLLY SINGH
DOLLY SINGH
SNEHA CHANDRA
SNEHA CHANDRA
SHRADHASWARUPA BISWAL
SHRADHASWARUPA BISWAL
SWASTIK DASH
SWASTIK DASH
TANIMA SAHOO
TANIMA SAHOO
Doctoral Students
Abhisek Jana
Thesis Submitted
Computer-Aided Drug Design (CADD)
Computational Investigation on Lysine
Methyltransferase G9a and Identification of Potential Epigenetic Inhibitors
Abhisek Jana
Thesis Submitted
Computer-Aided Drug Design (CADD)
Computational Investigation on Lysine
Methyltransferase G9a and Identification of Potential Epigenetic Inhibitors
Subhabrata Mabhai
Completed
Organic Synthesis and Chemical Sensors
Azo-based molecular probe for metal ion sensing
Subhabrata Mabhai
Completed
Organic Synthesis and Chemical Sensors
Azo-based molecular probe for metal ion sensing
Koushik Barman
Ongoing
Organic Synthesis and Medicinal Chemistry
Koushik Barman
Ongoing
Organic Synthesis and Medicinal Chemistry
Projects
Sl.No.
Title
Name of the PI
Name of the CoPIs
Funding Agency
Amount (Rs.)
Project Type
Project Status
Date of Initiation
Date of Completion
1
Chemical sensors cum inhibitors of Histone PTM
Dr Deb Ranjan Banerjee
Dr Sudipta Mondal
SERB-CRG
3,651,494
Sponsored
Ongoing
2022-12-30
2
NMR studies of Lys/Arg side chain interactions in epigenetics and membrane-induced dimerization
Deb Ranjan Banerjee
No
SERB-SIRE
712,000
Sponsored
Ongoing
Projects
Sl.No.
Title
Name of the PI
Name of the CoPIs
Funding Agency
Amount (Rs.)
Project Type
Project Status
Date of Initiation
Date of Completion
1
Chemical sensors cum inhibitors of Histone PTM
Dr Deb Ranjan Banerjee
Dr Sudipta Mondal
SERB-CRG
3,651,494
Sponsored
Ongoing
2022-12-30
2
NMR studies of Lys/Arg side chain interactions in epigenetics and membrane-induced dimerization
1. Neuroprotective effects of G9a inhibition through modulation of peroxisome-proliferator activator receptor gamma-dependent pathways by miR-128 Aina Bellver-Sanchis, Pedro A Ávila-López, Iva Tic, David Valle-García, Marta Ribalta-Vilella, Luis Labrador, Deb Ranjan Banerjee, Ana Guerrero, Gemma Casadesus, Coralie Poulard, Mercè Pallàs, Christian Griñán-Ferré Neural Regeneration Research
19(11):p 2532-2542
SCOPUS
10.4103/1673-5374.393102
2024
2024
2. G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease Aina Bellver-Sanchis, Qizhi Geng, Gemma Navarro, Pedro A. Ávila-López, Júlia Companys-Alemany, Laura Marsal-García, Raquel Larramona-Arcas, Lluisa Miró, Anna Perez-Bosque, Daniel Ortuño-Sahagún, Deb Ranjan Banerjee, Bhanwar Singh Choudhary, Francesc X Soriano, Coralie Poulard, Mercè Pallàs, Hai-Ning Aging and Disease
15(1): 311–337
SCOPUS
10.14336/AD.2023.0424-2
https://www.aginganddisease.org/EN/10.14336/AD.2023.0424-2
2024
2023
3. Theoretical Investigation on the Adsorption of Phospho-Tyrosine Derivatives Over Fe (1 1 0) Surface in 1 M HCl Medium Pradeep Kumar Rout, Tarun Roy, Deb Ranjan Banerjee, Utpal Adhikari, Dipankar Sukul, Subhas Ghosal Transactions of the Indian Institute of Metals
1-7
SCOPUS
10.1007/s12666-023-03152-4
5. Integration of ligand and structure-based pharmacophore screening for the identification of novel natureal leads against Euchromatic histone lysine methyltransferase 2 (EHMT2/G9a) Abhisek Jana, rahul Naga, Sougata Saha, Christian G-F, Deb Ranjan Banerjee Journal of Biomolecular Structure and Dynamics
SCOPUS
https://doi.org/10.1080/07391102.2023.2213346
2023
2022
6. 3D QSAR pharmacophore based lead identification of G9a lysine methyltransferase towards epigenetic therapeutics Abhisek Jana, rahul Naga, Sougata Saha, Deb Ranjan Banerjee Journal of Biomolecular Structure and Dynamics
SCOPUS
https://doi.org/10.1080/07391102.2022.2135600
Taylor&Francis
https://www.tandfonline.com/doi/abs/10.1080/07391102.2022.2135600
2022
2022
7. A naphthalene-based azo armed molecular framework for selective sensing of Al3+ Subhabrata Mabhai, Malay Dolai, Surya Kanta Dey, Sujata Maiti Choudhury, Bhriguram Das, Satyajit Dey, Atanu Jana, Deb Ranjan Banerjee New Journal of Chemistry
46, 6885-6898
SCI/SCOPUS
10.1039/D1NJ05869J
Royal Society of Chemistry
https://pubs.rsc.org/en/content/articlehtml/2022/nj/d1nj05869j
2022
2022
8. Computational investigation on natural quinazoline alkaloids as
potential inhibitors of the main protease (Mpro) of SARS_CoV_2 Abhisek Jana, Tarun Roy, Sarbajit Layek, Subhas Ghosal and Deb Ranjan Banerjee Journal of Computational Biophysics and Chemistry
Vol. 21, No. 01, pp. 65-82 (2022)
SCOPUS
https://doi.org/10.1142/S2737416522500053
https://www.worldscientific.com/doi/abs/10.1142/S2737416522500053
2022
2020
9. A cell-compatible red light-emitting multianalyte chemosensor via three birds, one stone strategy Subhabrata Mabhai, Malay Dolai, Surya Kanta Dey, Anamika Dhara, Sujata Maiti Choudhury, Bhriguram Das, Satyajit Dey, Atanu Jana, Deb Ranjan Banerjee* Journal of Photochemistry and Photobiology A: Chemistry
404
SCI
Elsevier
2020
2019
10. Acetylation of the histone H3 tail domain regulates base excision repair on higher-order chromatin structures. Scientific Reports, 2019, 9, 15972 Banerjee, D. R.; Deckard, C. E.; Zeng, Y.; Sczepanski, J. T. SCIENTIFIC REPORTS
9, 15972
SCOPUS
NATURE PUBLISHING GROUP
2019
2019
11. Chromatin Structure and the Pioneering Transcription Factor FOXA1 Regulate TDG-Mediated Removal of 5-Formylcytosine from DNA. J. Am. Chem. Soc. 2019 , 141 (36), 14110-14114 Deckard, C. E.; Banerjee, D. R.; Sczepanski, J. T. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
141 (36), 14110-14114
SCI
AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036
2019
2018
12. A Plug-and-Play approach for preparing chromatin containing site-specific DNA modifications: The influence of chromatin structure on base excision repair. J. Am. Chem. Soc., 2018, 140, 8260-8267 Banerjee, D. R.; Deckard, C. E.; Elinski, M.; Buzbee, M.; Wang, W. W.; Batteas, J. D. and Sczepanski J. T. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
140, 8260-8267
SCI
AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036
2018
2015
13. NMR (1H and 13C) based Signatures of Abnormal Choline Metabolism in Oral Squamous Cell Carcinoma with no Prominent Warburg Effect. Biochem. Biophys. Res. Commun., 2015, 459, 574-578 Bag, S*.; Banerjee, D. R*.; Basak, A.; Cheterjee, J. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
459, 574-578
SCI
ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495
2015
2015
14. Crystal structure of dehydratase component HadAB complex of mycobacterial FAS-II. Biochem. Biophys. Res. Commun., 2015, 458, 369-374 Biswas, R.; Dutta, A.; Dutta, D.; Hazra, D.; Banerjee, D. R.; Basak, A.; Das, A. K. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
458, 369-374
SCI
ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, USA, CA, 92101-4495
2015
2015
15. Inhibition of M. tuberculosis β-Ketoacyl CoA Reductase FabG4 (Rv0242c) by triazole linked polyphenol-aminobenzene hybrids: Comparison with the corresponding Gallate Counterparts. Bioorg. Med. Chem. Lett., 2015, 25, 1343-1347 Banerjee, D. R.; Senapati, K.; Biswas, R.; Das, A. K.; Basak, A. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
25, 1343-1347
SCI
PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OX5 1GB
2015
2015
16. Design, synthesis and characterization of dual inhibitors against new targets FabG4 and HtdX of Mycobacterium tuberculosis. Euro. J. Med. Chem., 2015, 100, 223-234 Banerjee, D. R.; Biswas, R.; Das, A. K.; Basak, A. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
100, 223-234
SCI
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 65 RUE CAMILLE DESMOULINS, CS50083, ISSY-LES-MOULINEAUX, FRANCE, 92442
2015
2014
17. pH sensitive fluorescent photoactive precursors: synthesis, photophysical, photochemical and biological applications. Org. Biomol. Chem., 2014, 12, 3459-69. Ikbal, M.; Saha, B.; Barman, S.; Atta, S.; Banerjee, D. R.; Ghosh, S. K.; Singh, N. D. P. ORGANIC & BIOMOLECULAR CHEMISTRY
12, 3459-69
SCI
ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE, ENGLAND, CAMBS, CB4 0WF
2014
2014
18. Design, synthesis and characterization of novel inhibitors against mycobacterial β-ketoacyl CoA reductase FabG4, Org. Biomol. Chem., 2014, 12, 73-85 Banerjee, D. R.; Dutta, D.; Saha, B.; Bhattacharyya. S.; Senapati, K.; Das, A. K.; Basak, A. ORGANIC & BIOMOLECULAR CHEMISTRY
12, 73-85
SCI
ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE, ENGLAND, CAMBS, CB4 0WF
2014
2014
19. Reversal of regioselectivity in acetylation and deacetylation of aryl-naphthalene diols and diacetates by amano lipase, RSC Advance, 2014, 4, 54235 Panja, A.; Banerjee, D. R.; Basak, A. RSC ADVANCES
4, 54235
SCI
ROYAL SOC CHEMISTRY, THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE, ENGLAND, CAMBS, CB4 0WF
2014
2013
20. Photocontrolled Nuclear-Targeted Drug Delivery by Single Component Photoresponsive Fluorescent Organic Nanoparticles of Acridin-9-Methanol, Bioconjugate Chem., 2013, 24, 1828-39 Jana, A.; Saha, B.; Banerjee, D. R.; Ghosh, S. K.; Nguyen, K. T.; Ma, X.; Qu, Q.; Zhao, Y.; Singh, N. D. P. BIOCONJUGATE CHEMISTRY
24, 1828-39
SCI
AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, USA, DC, 20036
2013
2010
21. Design, synthesis and reactivity of C2-symmetric azobenzene-based amino acid-bis(propargyl sulfones, Bioorg. Med. Chem. Lett., 2010, 20, 6831-5 Mitra, D.; Banerjee, D. R.; Das, A. K.; Basak, A. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
20, 6831-5
SCI
PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD, ENGLAND, OX5 1GB
2010
Conferences
ID
Details
Year
2023
1.A chemist’s dream to investigate epigenetics: A combined theoretical and experimental studies(International Symposium on Emerging trends in chemical science, ETCS-2023)
NEHU, SHILLONG, INDIA
2023
2023
2.Towards
epigenetic therapeutics using 3-I (in
silico, In vitro, In vivo)
Presidency University, Kolkata, India
2023
2018
3.‘Construction of designer chromatin with unique multi-functional DNA sequence: Effect of chromatin topology in base excision repair’ in 255th ACS National Meeting & Exposition, Division of Biological Chemistry, 2018, BIOL 295 (First author)
New Orleans, US
2018
2016
4.Construction and analysis of model chromatin systems containing specific DNA lesions’ in 252nd ACS National Meeting & Exposition, Division of Biological Chemistry, 2016, publication no 74 (First author)
Philadelphia, US
2016
2014
5.'First time inhibitors of Mycobacterium tuberculosis β-Ketoacyl CoA reductase FabG4 (rv0242c)’ in Daiichi Sankyo Co Limited-Royal Society of Chemistry (DSIN-RSC) joint conference in the topic of ‘Overcoming the Bottlenecks in Drug Discovery and Development’ (First Author)
Gurgaon, India
ERP
