Biotechnology

Faculty Details

Monidipa Ghosh Associate Professor
Joined the Institute in 2010
mghosh[dot]bt[at]nitdgp[dot]ac[dot]in
Publication

26

Publications

4

Sponsored Projects

0

Consultancy Projects
Education

6

Doctoral Students

0

UG Students

14

PG Dissertation
Education
  • Post Doctoral Research

Cell Biology and Immunology ,IICB, Jadavpur, Kolkata

  • PhD, Cell Biology and Immunology

The University of Jadavpur  (Indian Institute of Chemical Biology, Jadavpur)   

  • M.Sc. Zoology

University of Burdwan,WestBengal,India.

Work Experiences
  • Since 2010 Assistant Professor, Department of Biotechnology, N.I.T.

Durgapur, India.

  • Visiting Faculty in Department of Biotechnology,West Bengal University of Technology, (WBUT) Saltlake, Kolkata, 2008-2009.
Research Interest

Molecular Immunology, Nano-biotechnology and Biosensor development.

  1. Development and optimization of biosensors in disease diagnosis.
    Assessment of the biomarkers like HER2 and vitamin D in the detection of diseases 
    like breast cancer and obesity, cardiovascular, diabetic diseases respectively.
  2. Drug discovery and Nanotherapeutics
    Anti-parasitic effects of HMG CoA reductase inhibitor, statin and it’s immune-modulatory capacity. Silver nanoparticles are currently being investigated for their cytotoxic effect on different cancer cell lines. The mechanistic actions arealso matter of investigation.
  3. Parasite –Genomics
    Cloning and Functional analysis of different species-specific genes, expressed in Leishmania donovani.
  4. Host – Pathogen interactions and cell signaling
    Emphasis is given to the rapidly developing field of immunology in respect to the host's innate immune system interactions elicited by parasites.

 

  • Collaborative Research with the following institutes :

  1. IIT Kharagpur
  2. CMTI Bengaluru
Projects

 

Title Investigator Co-investigator Sponsered Agency Duration Status

1. Over riding Drug resistance in visceral leishaniasis by combitional therapy with sub optimal dose of HMG CoA reductase inhibitor, statin and trivalent chromium complex involving Src-family tyrosine kinase. DBT 2011-14,    Co-PI: SS Mukhopadhyay

2. Regulation of MCP-1-induced calcium-independent phospholipase A2 (IPLA2)-dependent monocyte migration. DBT 2019-22 , PI: A Bhattacharya

3. Evaluation of the role of Vitamin D in obesity , cardiovascular diseases and diabetes using SiOx/TiO2 nanowire based sensor. 2017-20, PI: A Mondal

4. Intel@ Movidius™ Neural Compute Stick Research Proposal ( A non-contact type health monitoring system development) . 2018-continuing. PI: C Koley

   Monidipa Ghosh DBT 2011-14 Completed

 

Teachings
  • Immunology (BT501)
  • Bioethics and IPR ( BT812)
  • Immunotechnology (BT9013 )
  • Industrial Production of Biopharmaceuticals (BT2003)
  • Immunology Lab(BT 552)

UG Students

Data Not Found!

PG Students

Data Not Found!

Doctoral Students

MOUMITA MAJI

MOUMITA MAJI

Ph.D. (Submitted)
MOUMITA MAJI

MOUMITA MAJI

Ph.D. (Submitted)
BAPI BISWAS

BAPI BISWAS

Ph.D. (Completed)
BAPI BISWAS

BAPI BISWAS

Ph.D. (Completed)
Sagarika Deepthy

Sagarika Deepthy

Ph.D. (Completed)
Sagarika Deepthy

Sagarika Deepthy

Ph.D. (Completed)
Suvadip Saha

Suvadip Saha

Ph.D. (Ongoing)
Suvadip Saha

Suvadip Saha

Ph.D. (Ongoing)
AMIT KUMAR VERMA

AMIT KUMAR VERMA

Ph.D. (Completed)
AMIT KUMAR VERMA

AMIT KUMAR VERMA

Ph.D. (Completed)
BHAKTI LAHA

BHAKTI LAHA

Ph.D. (Completed)
BHAKTI LAHA

BHAKTI LAHA

Ph.D. (Completed)

Projects

Sl.No. Title Name of the PI Name of the CoPIs Funding Agency Amount (Rs.) Project Type Project Status Date of Initiation Date of Completion
1 Identification of anti-leishmanial molecules acting as novel inhibitors against intracellular lipid signaling machinery in Leishmania donovani Ghosh M. K. Pandey, K. Das, A. Sen, A. Barik I.C.M.R. Gov. of India 531,800 Sponsored Ongoing 2023
2 Engineering of cellulase enzymes of Aspergillus fumigatus NITDGPKA3 for enhancing their activity Mukhopadhyay, S.S. Aikat, K. Department of Biotechnology (DBT), Govt. of India 3,763,000 Sponsored Completed 2017-06-10 2020
3 Evaluation of the role of Vitamin D in obesity, Cardiovascular Disease and diabetes using Siox/Tio2 nanowire based sensor. Manndal A. Ghosh M. SERB, DST. Gov. of India 4,890,000 Sponsored Completed 2017 2020
4 Overriding Drug resistance in visceral leishaniasis by combitional therapy with sub optimal dose of HMG CoA reductase inhibitor, statin and trivalent chromium complex involving Src-family tyrosine kinase. Ghosh M. S.S. Mukhopadhyay Rapid Grant for Young Investigator (RGYI). Department of Biotechnology (DBT), Gov. of India 2,560,000 Sponsored Completed 2011 2014

Projects

Sl.No. Title Name of the PI Name of the CoPIs Funding Agency Amount (Rs.) Project Type Project Status Date of Initiation Date of Completion
1 Identification of anti-leishmanial molecules acting as novel inhibitors against intracellular lipid signaling machinery in Leishmania donovani Ghosh M. K. Pandey, K. Das, A. Sen, A. Barik I.C.M.R. Gov. of India 531,800 Sponsored Ongoing 2023
2 Engineering of cellulase enzymes of Aspergillus fumigatus NITDGPKA3 for enhancing their activity Mukhopadhyay, S.S. Aikat, K. Department of Biotechnology (DBT), Govt. of India 3,763,000 Sponsored Completed 2017-06-10 2020
3 Evaluation of the role of Vitamin D in obesity, Cardiovascular Disease and diabetes using Siox/Tio2 nanowire based sensor. Manndal A. Ghosh M. SERB, DST. Gov. of India 4,890,000 Sponsored Completed 2017 2020
4 Overriding Drug resistance in visceral leishaniasis by combitional therapy with sub optimal dose of HMG CoA reductase inhibitor, statin and trivalent chromium complex involving Src-family tyrosine kinase. Ghosh M. S.S. Mukhopadhyay Rapid Grant for Young Investigator (RGYI). Department of Biotechnology (DBT), Gov. of India 2,560,000 Sponsored Completed 2011 2014

Projects

Sl.No. Title Name of the PI Name of the CoPIs Funding Agency Amount (Rs.) Project Type Project Status Date of Initiation Date of Completion
Indexing

13

Google Scholar h-index

14

Google Scholar i10-index

0

Scopus h-index

Journals

ID Details Year
December 2014 1.  Comparative in-silico genome analysisof Leishmania(Leishmania) donovani: A step towards its species specificity,,  , Pages 782-798. Satheesh Kumar S,.GokulasuriyanR.K. ,MonidipaGhosh*. Meta Gene 2 SCI December 2014
2022 2. Kinetic modelling of high concentration 4-Nitrophenol biodegradation by an isolated bacterial consortium and post-treatment ecotoxicity analysis Apurba Dey Priyanka Sarkar, Moumita Maji, Monidipa Ghosh Biocatalysis and Agricultural Biotechnology  SCI/SCOPUS https://doi.org/10.1016/j.bcab.2022.102316 Elsevier 2022
2022 3. Study of microstructural and electrical properties of silver substituted hydroxyapatite for drug delivery applications Tuli Chatterjee, Moupiya Ghosh, Moumita Maji, Monidipa Ghosh, Swapan Kumar Pradhan, Ajit Kumar Meikap Materials Today Communications SCI/SCOPUS https://doi.org/10.1016/j.mtcomm.2022.103360 Elsevier https://www.sciencedirect.com/science/article/pii/S2352492822002318 2022
2020 4. Detection technique for vitamin D3 using Er-doped TiO2 nanowire-based UV photodetector Shyam Murli Manohar Dhar Dwivedi, Anupam Ghosh, Sagarika Deepthy, Moumita Maji, Rini Lahiri, Sanjib Mondal, Chiranjib Ghosh, Avijit Dalal, Aniruddha Mondal, Monidipa Ghosh Journal of Nanophotonics SCI/SCOPUS 10.1007/s11468-021-01509-3 SPIE 2020
2020 5. Identification and characterisation of the gene encoding an amastine-like surface protein (ALSP) in the Leishmania donovani genome: a putative anti-leishmanial drug target B Biswas, B Laha, M Ghosh* BioRxiv . Others . . 2020
2020 6. Unveiling the cytotoxicity of phytosynthesised silver nanoparticles using Tinospora cordifolia leaves against human lung adenocarcinoma A549 cell line Jitendra Mittal, Uttariya Pal, Lakshika Sharma, Amit Kumar Verma, Monidipa Ghosh, Madan Mohan Sharma IET Nanobiotechnology 14 SCI IET Digital Library 2020
2020 7. Integrated Bioinformatics Analysis Deciphering the microRNA Regulation in Protein-Protein Interaction Network in Lung Adenocarcinoma P Sengupta, S Saha, M Maji, M Ghosh BioRxiv . Others . Pre-print Server 2020
2019 8. Detection and characterization of an albumin-like protein in Leishmania donovani. Laha B , Verma AK , Biswas B , Sengodan SK , Rastogi A , Willard B , Ghosh M * Parasitology Research [22 Mar 2019, 118(5):1609-1623] SCI 10.1007/s00436-019-06286-x Europe PMC 2019
2017 9. Development of screen-printed electrode based immunosensor for the detection of HER2 antigen in human serum samples Sagarika Deepthy Tallapragada, Keya Layek, Runu Mukherjee, Kalyan Kumar Mistry, Monidipa Ghosh Bioelectrochemistry SCI/SCOPUS https://doi.org/10.1016/j.bioelechem.2017.06.009 Elsevier https://www.sciencedirect.com/science/article/pii/S1567539416302584 2017
2013 10. Investigation on bacterial adhesion and colonisation resistance over laser-machined micro patterned surfaces Aneissha Chebolu, Bhakti Laha, Monidipa Ghosh Micro & Nano Letters SCI/SCOPUS https://doi.org/10.1049/mnl.2013.0109 The Institution of Engineering and Technology https://ietresearch.onlinelibrary.wiley.com/doi/pdf/10.1049/mnl.2013.0109 2013
2009 11. N-acetyl cysteine enhances imatinib-induced apoptosis of Bcr-Abl+ cells by endothelial nitric oxide synthase-mediated production of nitric oxide Srabanti Rakshit, Jayashree Bagchi, Labanya Mandal, Kausik Paul, Dipyaman Ganguly, Sandip Bhattacharjee, Monidipa Ghosh, Nabendu Biswas, Utpal Chaudhuri, Santu Bandyopadhyay Apoptosis SCI/SCOPUS https://doi.org/10.1007/s10495-008-0305-7 Springer US https://link.springer.com/article/10.1007/s10495-008-0305-7 2009
2006 12. Leishmania donovani Infection of Human Myeloid Dendritic Cells Leads to a Th1 Response in CD4+ T Cells from Healthy Donors and Patients with Kala-Azar Monidipa Ghosh, Labanya Mandal, Sudipta Maitra, Srabanti Rakshit, Kausik Paul, Jayashree Bagchi, Dipyaman Ganguly, Chiranjib Pal, Santu Bandyopadhyay The Journal of infectious diseases SCI/SCOPUS https://doi.org/10.1086/505228 The University of Chicago Press https://academic.oup.com/jid/article/194/3/294/900369 2006
2004 13. Interaction of Leishmania parasites with dendritic cells and its functional consequences Monidipa Ghosh, Santu Bandyopadhyay Immunobiology SCI/SCOPUS https://doi.org/10.1016/j.imbio.2004.02.007 Urban & Fischer https://www.sciencedirect.com/science/article/pii/S0171298504000099 2004
2003 14. Present status of antileishmanial vaccines Monidipa Ghosh, Santu Bandyopadhyay Molecular and cellular biochemistry SCI/SCOPUS https://doi.org/10.1023/A:1026047429604 Kluwer Academic Publishers https://link.springer.com/content/pdf/10.1023/A:1026047429604.pdf 2003
2003 15. Dendritic Cell-Based Immunotherapy Combined with Antimony-Based Chemotherapy Cures Established Murine Visceral Leishmaniasis Monidipa Ghosh, Chiranjib Pal, Mitali Ray, Sudipta Maitra, Labanya Mandal, Santu Bandyopadhyay The Journal of Immunology SCI/SCOPUS https://doi.org/10.4049/jimmunol.170.11.5625 American Association of Immunologists https://www.jimmunol.org/content/jimmunol/170/11/5625.full.pdf 2003
2003 16. Dihydrobetulinic Acid Induces Apoptosis in Leishmania donovani by Targeting DNA Topoisomerase I and II: Implications in Antileishmanial Therapy Arnab Roy Chowdhury, Suparna Mandal, Anindya Goswami, Monidipa Ghosh, Labanya Mandal, Debabani Chakraborty, Agneyo Ganguly, Gayatri Tripathi, Sibabrata Mukhopadhyay, Santu Bandyopadhyay, Hemanta K Majumder Molecular Medicine Vol 9 pages 26-36 SCI/SCOPUS https://doi.org/10.1007/BF03402104 BioMed Central https://link.springer.com/article/10.1007/BF03402104 2003
2002 17. Combination Therapy with Indolylquinoline Derivative and Sodium Antimony Gluconate Cures Established Visceral Leishmaniasis in Hamsters Chiranjib Pal, Mousumi Raha, Anirban Basu, Keshab Chandra Roy, Anasuya Gupta, Monidipa Ghosh, Niranjan Prasad Sahu, Sukdeb Banerjee, Nirup Bikash Mandal, Santu Bandyopadhyay Antimicrobial agents and chemotherapy SCI/SCOPUS https://doi.org/10.1128/AAC.46.1.259-261.2002 American Society for Microbiology https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126984/ 2002
2002 18. Synthesis of a novel quinoline derivative, 2-(2-methylquinolin-4-ylamino)-N-phenylacetamide—a potential antileishmanial agent Niranjan P Sahu, Chiranjib Pal, Nirup B Mandal, Sukdeb Banerjee, Mausumi Raha, Ashis P Kundu, Anirban Basu, Monidipa Ghosh, Keshab Roy, Santu Bandyopadhyay Bioorganic & medicinal chemistry Vol 10 pages 1687-1693 SCOPUS https://doi.org/10.1016/S0968-0896(02)00046-9 Pergamon https://www.sciencedirect.com/science/article/pii/S0968089602000469 2002
2001 19. Characterisation of the gene encoding type II DNA topoisomerase from Leishmania donovani: a key molecular target in antileishmanial therapy Aditi Das, Arindam Dasgupta, Shalini Sharma, Monidipa Ghosh, Tanushri Sengupta, Santu Bandopadhyay, Hemanta K Majumder Nucleic acids research SCI/SCOPUS https://doi.org/10.1093/nar/29.9.1844 Oxford University Press https://academic.oup.com/nar/article/29/9/1844/2384079 2001

Conferences

ID Details Year

Books

ID Title

Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics. By Sayak Roychowdhury and Dr. Monidipa Ghosh*

 1.

Next-Generation Nanobiosensor Devices for Point-Of-Care Diagnostics. By Sayak Roychowdhury and Dr. Monidipa Ghosh*

Smart nanobiosensing for COVID-19 diagnosis

 2.

Smart nanobiosensing for COVID-19 diagnosis

An IoT enabled Enzyme Embossed Biosensor for Determination of Vitamin D Level in Human Blood Sample. By Monidipa Ghosh* and Chiranjib Koley                        Published by Spinger Nature 

 3.

An IoT enabled Enzyme Embossed Biosensor for Determination of Vitamin D Level in Human Blood Sample. By Monidipa Ghosh* and Chiranjib Koley                        Published by Spinger Nature 

Patents

ID Details Patent Filed Year
2019 1. An Electrode based system for analysis of Biomarkers\Biological specimens  File No. 2019310472 03 0 Monidipa Ghosh, Chiranjib Koley Submitted 2019
2019 2. A system for measurement of Vitamin D level in serum samples. Dr. Monidipa Ghosh, Chiranjib Koley, Doel Pal, Moumita Maji, Sourav Dhara. Submitted 2019
2019 3. Amorphous silicon mono oxide-based nanowire electrode biosensor. Dr. Aniruddha Mondal; Dr. Monidipa Ghosh; Shyam Murli Manohar Dhar Dwivedi, Dr. Chiranjib Ghosh; Sagarika Deepthy, Rini Lahiri. Submitted 2019
1959 4. US Patent Granted. An in vitro method to generate dendritic Langerhans type cells.S. Bandyopadhyay, K.C. Roy, M. Ghosh, M. Ray, C. Pal and S. Bhattacharya. (Council of Scientific and Industrial Research, India.)Patent No: US 7,638,329 B2. Date of Patent: Dec. 29, 2009.   Submitted 1959
Awards and Recognitions

1. Young Investigator Award 2003, awarded by European Macrophage

    Dendritic cell and Society , Organised by University of Leicester, UK, 

    2003.

2. Nominated for INSA Young Scientist’s award, 2004.

3. All India Rank 127 in GATE, Ministry of Human Resource  Development, 

    Government of India, 1998.

4. National Scholarship and Merit Certificate, 1988 & 1990. Ministry of

     Human Resource Development, Government of India. (Bellow 40 rank 

     in Board Exams).

5. Chaired the session of World Congress On Drug Discovery And

     Development  at I.I.Sc. Bangalore. 2016.

6. International Travel Award , SERB, Gov. of India, for participating in

     World Immune Regulation Meeting VII , Davos,  Switzerland, 2013,

7.Reviewed Thesis ( The West Bengal University of Health Sciences) on

    2015.

Administrative Responsibilities

Sl.No.

Section /office/Institute level committee

From

To

Position held

Responsibilities

 
1.  Department of Biotechnology 2019 Continuing PG Coordinator PG Course coordination
2. Institutional Ethical Committee for Human Research 2017 Continuing Member Secretary Coordinating meetings 

3.

Hall 10, hall 6, Girls' Hostels

June 2013

2017

Warden

Monitoring Hostel matters.
4.

Dept. of Biotechnology, NIT DGP.

2013

2019

Departmental Training and Placement officer.

Co-ordination between institutional TPC and Dept. Biotech.

5.

NIT DGP Dept. of Biotechnology

2012

2019

In the Organising committee of Biotechnology Society.

 

Do

6.

NIT DGP Dept. of Biotechnology

2012

2018

Member of Departmental purchase committee for TEQIP, New Building shifting and management committee

Maintaining the purchase procedure properly.  and Management for shifting in new building

 

Contact


Email : mghosh.bt@nitdgp.ac.in, gmonidipanitd@gmail.com

Academic Identity

Orcid Id
Scopus Id
Researcher Id
Google Scholar Id